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How do you tune a Node.js app for low latency?

Senior NodeJS
Quick Answer Low latency tuning: use keep-alive connections (avoid TCP reconnects), disable Nagle's algorithm (socket.setNoDelay), use fast JSON parsers (fast-json-stringify, oj), avoid synchronous I/O, keep event loop free of heavy work (worker threads for CPU tasks), pre-warm the JIT (run warmup requests on startup), and profile with clinic.js flamegraphs.

Answer

Avoid blocking operations, reduce GC pauses, use streams, optimize DB queries, enable keep-alive, and minimize middleware overhead.
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